Mastocytosis Society Canada

Systemic Mast Cell Disease: An Update as of June, 2011

We would like to thank Dr. Afrin for his review and editing of this transcript. This document is current as of June, 2011, for suggested diagnosing and treating mastocytosis and mast cell activation disorder.

Dr. Afrin also generously inserted his slides sequentially throughout the transcript.

Due to the large file size of the final document, we are providing two versions for viewing, download, free sharing and distribution for educational purposes worldwide. We encourage patients and caregivers to share this document (via download or sharing a link to this page) with all of your doctors.

(Note: Our FAQ page is complete. The remainder of this section of our website will be updated in the near future. For now, this document covers the topic and subsections for systemic mastocytosis and mast cell activation syndrome.)

Abstract: On June 6, 2011, Mastocytosis Society Canada, meeting at the University of Toronto, hosted a talk by Lawrence B. Afrin, M.D. (Associate Professor of Medicine, Division of Hematology/Oncology, Medical University of South Carolina) on recent developments in our understanding of systemic mast cell disease. Dr. Afrin's presentation focused largely on "mast cell activation syndrome," a relatively newly defined entity in the spectrum of mast cell diseases which now appears to be far more prevalent than the long-recognized (but rare) "mastocytosis." With the help of a number of illustrative cases woven into his presentation, Dr. Afrin described the extreme variability of mast cell disease from patient to patient and how mast cell disease can affect every system, organ, and tissue in the body. Toward the end of the presentation, he provided some basic suggestions that may help in diagnosing and treating the disease. Dr. Afrin suggests that professionals interested in reading a more concise review of mast cell activation disease before tackling this presentation may wish to peruse: Molderings GJ, Brettner S, Homann J, Afrin L. Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options. J Hematol Oncol 2011, 4:10, doi:10.1186/1756-8722-4-10, available at http://www.jhoonline.org/content/4/1/10.

View/Download full transcript with slides PDF (153 pages; 26 MB):-
Transcript of MSC Medical Lecture June, 2011, with slides **large file; approximately 1 minute to load and open

View/Download transcript without slides PDF (40 pages; 729 KB):-
Text only Transcript of MSC Medical Lecture June, 2011

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